Manipal Institute of Neuro Sciences Introduces Adaptive Deep Brain Stimulation for Movement Disorders

The system has been installed at the Manipal Hospital Sarjapur Road facility and uses real-time brain activity monitoring to automatically adjust stimulation levels.

The Manipal Institute of Neuro Sciences has introduced Adaptive Deep Brain Stimulation (aDBS) services at its dedicated DBS Clinic in Bengaluru, expanding treatment options for patients with movement disorders and neurological conditions.

The system has been installed at the Manipal Hospital Sarjapur Road facility and uses real-time brain activity monitoring to automatically adjust stimulation levels. The technology analyzes biomarkers in the patient’s brain to modify therapy based on changing symptoms, offering a personalized treatment approach.

Unlike traditional deep brain stimulation, which operates at a fixed stimulation level throughout the day, adaptive DBS continuously responds to a patient’s neural signals. The system uses BrainSense technology to detect beta wave patterns associated with movement symptoms and adjusts stimulation accordingly.

According to clinicians, the system increases stimulation during symptom flare-ups, such as tremors or rigidity associated with Parkinson’s disease, while reducing intensity during stable periods like rest or sleep. This adaptive response aims to optimize therapy delivery and minimize unnecessary stimulation.

Clinical studies have shown that adaptive DBS can reduce motor fluctuations and improve quality of life compared to conventional DBS. The technology also consumes less power overall while maintaining symptom control.

The introduction of aDBS expands the treatment pathway at the hospital’s DBS Clinic, which provides evaluation, advanced stereotactic neurosurgery, intraoperative neuromonitoring, device implantation, and long-term programming support for patients undergoing deep brain stimulation therapy.

Patients with Parkinson’s disease who experience limited response to medications may benefit from the therapy. Clinical evidence suggests that deep brain stimulation can improve motor symptoms and functional outcomes in eligible patients.

The DBS Clinic at the hospital operates weekly on Wednesdays from 9:00 am to 12:00 noon, offering consultations for patient assessments, counselling, and caregiver guidance.

“Adaptive DBS activation empowers us to deliver truly responsive therapy, transforming lives for those battling advanced movement disorders,” said Dr Shivakumar, Lead Consultant, Neurology.

“This milestone underscores our commitment to personalised stimulation and patient-centred innovation,” added Dr Ajay Hegde, Consultant Neurosurgeon at the hospital.

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