SigTuple Launches AS76 AI Digital Morphology Analyzer for Labs

The system combines digital microscopy with edge-AI computing to deliver rapid, consistent results while maintaining patient data privacy.

Bengaluru-based SigTuple has launched AS76, an AI-enabled digital morphology analyzer designed to automate peripheral blood smear (PBS) review. The system combines digital microscopy with edge-AI computing to deliver rapid, consistent results while maintaining patient data privacy.

Powered by NVIDIA RTX, AS76 performs high-throughput image analysis entirely on-device, eliminating reliance on internet connectivity. The system can scan up to six PBS slides simultaneously, generating AI-assisted reports for expert review. Key features include automated 200-cell leukocyte differentials, red blood cell morphology assessment, and platelet morphology evaluation, including detection of platelet aggregates.

AS76 is equipped with 20×, 40×, and 100× objectives on an automated turret. While it currently focuses on peripheral blood smears, the platform is designed for future software upgrades to support tissues, fluids, bone marrow, and microbiology slides, positioning it as a digital alternative to conventional microscopes.

By leveraging AI-driven cell pre-classification, AS76 standardizes smear review at scale and highlights atypical findings for expert confirmation. Local AI processing ensures near-instant results, reduces manual workload, shortens turnaround times, and keeps patient data within the laboratory. The system is CE-marked under IVDR, demonstrating compliance with European safety and performance standards.

SigTuple’s AI-based microscopy solutions have previously improved access to specialist expertise in underserved areas, enabling centralized pathologist review, timely diagnosis, and early detection of critical conditions. AS76 builds on this foundation, combining advanced imaging and edge AI to expand high-quality diagnostics to more laboratories and patients.

“Edge AI is the future of diagnostic microscopy,” said Tathagato Rai Dastidar, Founder & CEO of SigTuple. “With AS76, intelligence stays where data is generated, delivering near-instant analysis while preserving patient privacy. Labs gain speed and consistency, and patients gain confidentiality.”

Tobias Halloran, Director of EMEAI Startups and Venture Capital at NVIDIA, added, “NVIDIA is accelerating India’s AI startup ecosystem by providing access to scalable AI infrastructure and programs that help startups scale faster and build for global markets.”

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