Amazon One Medical Launches Agentic Health AI Assistant for Personalized Care

The AI-powered assistant is now available to all One Medical members, providing round-the-clock support tailored to a patient’s medical history, lab results, and current medications.

Amazon One Medical has launched an AI-powered Health Assistant designed to simplify access to care and deliver personalized, actionable health guidance through the One Medical app. The AI-powered assistant is now available to all One Medical members and provides round-the-clock support based on a patient’s medical history, lab results, and current medications.

According to the company, the Health AI assistant is built to help patients navigate routine health needs while ensuring timely connection to clinicians when medical expertise is required. The tool can answer general and complex health questions, explain lab results in the context of an individual’s health record, recommend appropriate care options, and assist with booking virtual or in-person appointments, including same- or next-day visits. It also supports medication renewals, with the option to fill prescriptions through Amazon Pharmacy.

Amazon stated that the assistant has been developed in close collaboration with One Medical’s clinical leadership, with multiple safety and clinical guardrails embedded throughout the experience. The system is designed to recognize symptoms or scenarios that require human clinical judgment and prompts patients to connect with their care team via secure messaging, video visits, or in-person consultations.

Neil Lindsay, senior vice president of Amazon Health Services, said the assistant addresses fragmentation in the US healthcare system by bringing together patient health information in one place to support informed decision-making and easier access to care.

The Health AI assistant draws insights from a patient’s complete One Medical record, including past conditions, test results, vaccinations, and medications, without requiring manual uploads from external providers. Amazon emphasized that the assistant operates under HIPAA-compliant privacy and security standards. Conversations with the AI are not automatically added to medical records, and health data is protected through encryption and strict access controls. The company stated that it does not sell members’ personal health information.

Dr. Andrew Diamond, chief medical officer at One Medical, said the tool is intended to complement—not replace—the patient-clinician relationship, supporting patients in understanding their health information and managing routine tasks while ensuring clinicians remain central to care delivery.

The Health AI assistant was previously available to a limited group of members in beta beginning in early 2025. Amazon One Medical said it has incorporated feedback from both patients and clinicians and plans to continue expanding the assistant’s capabilities over time.

The assistant is powered by AI models hosted on Amazon Bedrock and is accessible directly within the One Medical app. Members who choose not to use the feature can continue using the standard app experience.

Stay tuned for more such updates on Digital Health News