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Redcliffe Labs Sets Precise Metrics to Help Identify PCOS More Accurately

Written by : Aishwarya Sarthe

September 20, 2023

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These precise metrics empower healthcare professionals with a highly accurate tool to identify PCOS in their patients efficiently and promptly. This precise approach holds great promise to streamline PCOS diagnosis, facilitating timely interventions and treatments.

Redcliffe Labs, under the guidance of Dr. Sohini Sengupta, the medical laboratory director, has made significant developments in women's health research. The company conducted a study focusing on Indian women to  define a diagnostic threshold for Polycystic Ovarian Syndrome (PCOS). 

The study, 'œEstablishment of age-specific reference intervals for AMH in Indian women and enhancing its use as a diagnostic marker in PCOS' aimed to establish specific age-related benchmarks for Anti-Mullerian Hormone (AMH) and define a diagnostic threshold for Polycystic Ovarian Syndrome (PCOS). PCOS affects about 11.34% of women in India; hence, improving its diagnosis is crucial.

The study analysed almost 2,000 samples collected from Indian women. The findings suggest that the optimal AMH cut-off point for diagnosing PCOS in the Indian female population is 7.51 ng/ml. 

This newly identified diagnostic threshold demonstrates an impressive sensitivity of 99.4% and specificity of 95.5 %. 

These precise metrics empower healthcare professionals with a highly accurate tool to identify PCOS in their patients efficiently and promptly. This precise approach holds great promise to streamline PCOS diagnosis, facilitating timely interventions and treatments.

Dr. Sohini Sengupta, discussing the findings, said, "Our findings represent a significant leap toward population-specific healthcare in India. They will facilitate the diagnosis and treatment of PCOS and lay the groundwork for future research focused on localized medical data."

As per the study abstract, the Anti-mullerian hormone (AMH) level is a dependable indicator of a woman's ovarian reserve, revealing the number of eggs in her ovaries. It's recognised that several factors, including age, ethnicity, and ovarian health can influence AMH levels. Given these influences, establishing specific AMH reference ranges for different age groups and nationalities is highly significant for effective healthcare.

As per the study, AMH levels are higher in women with polycystic ovary syndrome (PCOS). A population-specific cut-off point for AMH is crucial to enable healthcare practitioners to use it as a diagnostic tool for PCOS in women. This approach enhances precision in diagnosing PCOS, a condition affecting many women in India.

Furthermore, the research has been published in the International Journal of Reproduction, Contraception, Obstetrics, and Gynecology (IJRCOG), adding to its credibility and potential impact.

Redcliffe Labs, founded in 2018 in Noida, is expanding its diagnostic network. As per the company, with more than 3600 tests available across 80+ labs and 2000+ collection centres, 50,000+ Indian doctors trust it, and it processes more than 250,000 test parameters daily. 


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